Wednesday, April 10, 2024

What Antibiotics Are Used For Prostatitis

How Will Your Doctor Diagnose A Prostate Infection

What Is Prostatitis? Symptoms, Causes, Treatment & Antibiotics

A prostate infection diagnosis is based on your medical history, a physical exam, and medical tests. Your doctor can also rule out other serious conditions such as prostate cancer during the exam. During a physical exam, your doctor will conduct a digital rectal exam to test your prostate and will look for:

  • discharge
  • enlarged or tender lymph nodes in the groin
  • swollen or tender scrotum

Your doctor may also ask about your symptoms, recent UTIs, and medications or supplements youre taking. Other medical tests that can help your diagnosis and treatment plan include:

  • urinalysis or semen analysis, to look for infections
  • a prostate biopsy or a blood test for prostate-specific antigen
  • urodynamic tests, to see how your bladder and urethra store urine
  • cystoscopy, to look inside the urethra and bladder for blockage

Your doctor may also order an ultrasound to get a closer look. The cause will help determine the correct course of treatment.

Treatment Of Bacterial Prostatitis

The approach to treating bacterial infection of the prostate largely centers on appropriately selected antibiotic therapy. The best approach to treating nonbacterial prostatitis is less clear.

Overview of antibiotic therapy. Treatment of bacterial prostatitis is hampered by the lack of an active antibiotic transport mechanism and the relatively poor penetration of most antibiotics into infected prostate tissue and fluids. Most antibiotics are either weak acids or bases that ionize in biological fluids, which inhibits their crossing prostatic epithelium . Only free, non-protein-bound antibiotic molecules enter tissues. Ordinarily, substances with molecular weights of < 1000 pass through openings between capillary endothelial cells, but prostate capillaries are nonporous. Passage of a drug through prostatic capillary endothelium and prostatic epithelium is enhanced by a high concentration gradient, high lipid solubility, low degree of ionization, high dissociation constant , low protein binding, and small molecular size . A pH gradient allows electrically neutral molecules to pass through membranes, become ionized, and be trapped. Although ion trapping may increase prostatic drug concentration, the charged fraction has an unclear antimicrobial role. Fluoroquinolones are zwitterions that have a different pKa in an acidic versus an alkaline milieu, allowing concentrations in the prostate to be 10%50% of concentrations in serum .

Alternative Traditional Chinese Medicine Treatment For Prostatitis :

Dr.Mingâs Formulated Traditional Chinese Medicine Nanke Pills are Prescribed to the Patients Suffering From Prostatitis , Acute Prostatitis , Acute Bacterial Prostatitis , Chronic Bacterial Prostatitis , CPPS â Chronic Pelvic Pain Syndrome , BPH Benign Prostate Hyperplasia , Prostate calcification .

TCM Directions of Usage for Prostatitis : The Medication comes in A Solid Balls Form with Herbal Odor and small size , Depending on the Severity and the Combination of the Diseases the Medication is Prescribed to the Patients , Usually Treatment may last for 3-6-9 Months Depending on the Severity of the disease .The oral medication Nanke Pills can be taken twice a day may differ between patients due to different health conditions .Please contact Dr.Ming For the Prescription for the Medication .

TCM Proatatitis Medicine Is Prescribed for :ï¬ Prostatitis

You can Not Take Traditional Chinese Medicine For Prostatitis If You are Suffering From :ï¬ Severe Heart Conditionsï¬ Digestive Problemsï¬ Kidney Problems

Please Consult Dr.Ming Before If you are suffering from any conditions in the above mentioned list .

Contact Dr.Ming with your Detailed Disease History Including Your Age , Symptoms , Previous Infections , So that Dr.Ming can diagnose Perfectly and Provide you with the Best Traditional Chinese Medicine Treatment Option .

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What Are The Complications Of Prostatitis

Men with acute bacterial prostatitis may develop . This widespread inflammation can be life-threatening. It requires immediate medical treatment.

Antibiotics can cause an upset stomach. Men with chronic bacterial prostatitis may need lots of antibiotics to treat recurring infections. Some people develop antibiotic resistance, making treatment ineffective.

Asymptomatic inflammatory prostatitis can lower sperm count, affecting fertility.

Chronic Prostatitis Treatment Evolution At The Prostate Institute Of America

Acute Prostatitis

Antibiotics are the most important and main component in my medication treatment mixture. Infection caused by gram negative bacteria is the most common cause of bacterial prostatitis/urinary tract infection. As a result, I have used Fluoroquinolone and Gentamicin as the main antibiotics for a long period of time with variable clinical success.

It has become apparent that most of my patients have been exposed to Fluoroquinolones for extended periods of time before they come to get the treatment here. Easy access, oral formulary availability, and broad-spectrum coverage have led to widespread and improper use of Fluoroquinolones. Subsequently, resistance against Fluoroquinolones have developed worldwide.

A few years ago, I replaced Fluoroquinolone with Cephalosporin in the treatment mixture. Ceftriaxone is a broad-spectrum antibiotic, and has less chance of overuse and improper use since it can only be administered only intramuscularly or intravenously. In my personal experience I have noticed slightly better results clinically.

ESBLs have been found exclusively in gram-negative organisms, particularly Escherichia coli and Klebsiella, but also in Acinetobacter, Enterobacter, Proteus, Pseudomonas, Salmonella, and Shigella.

Community and hospital-acquired ESBL-producing gram negative bacteria are prevalent worldwide. Antibiotics from the Carbapenem family are the best anti-microbial agents to treat infections caused by such organisms.

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Antibiotics For Prostatitis: Why They Dont Work

I went to my urologist and he prescribed me 4 weeks of ciprofloxacin. I have taken the full course, yet my prostatitis symptoms have not shown any signs of improvement. The urologist is saying its probably non-bacterial prostatitis.

My urologist diagnosed me with prostatitis and prescribed me 2 weeks of doxycycline. My symptoms became much better by the 5th day. But they gradually started coming back again. It has now been a month since the doxy course ended, and my symptoms are back to what they were before taking the antibiotic.

My urologist prescribed levofloxacin for 4 weeks to treat my prostatitis. After 2 weeks of the antibiotic, my symptoms were completely resolved. I thought my prostatitis was cured! However, a few weeks after finishing the levofloxacin, my symptoms started reappearing. 2 months later, I was back to square one.

For my prostatitis, I have had five different antibiotics, some orally and some intravenously. After each course of antibiotics, I would go back to my urologist with little to no improvement, and he would prescribe me a different antibiotic. Today, after all these antibiotics, I am no better than I was when my problem started.

1. The poor vascularity of the prostate gland
2. Poor penetration of antibiotics through the outer membrane of the prostate
3. Evolution of the bacteria to form antibiotic resistance
4. Prostatitis is a Biofilm infection

Bactrim Prostatitis Antibiotic :

The Antibiotic is a Combination of Other Drugs which is Prescribed to Patients suffering from Acute Bacterial Prostatitis , Chronic Bacterial Prostatitis .Directions of Usage of Bactrim For Prostatitis : The Antibiotic is Available In 2 Different Forms Liquid and Tablet The Tablet Form Usually taken Twice a Day which Contains 800mg sulfamethoxazole and 160 mg trimethoprim Itâs a Double Formula Medication .The Liquid form Contains 200 mg sulfamethoxazole and 40 mg trimethoprim per 5 mL and The usage depends on the Directions Prescribed by the Physician .Bactrim Prescribed For : The Bactrim is Prescribed By Physician for the Following Infections Which include :ï¬ Ear Infection

ï¬ Mouth Sores

Does Bactrim Can Cure Prostatitis?Bactrim is Prescribed for the Patients Suffering from Bacterial Infections , which can ease the pain of the patients and may give relief from the symptoms .The Bactrim is Usually Prescribed for 4-6 Weeks , If patients doesnât Recover from the Symptoms or Bacterial Infection other set of antibiotics are prescribed accordingly . 96% Patients returns to the Clinic Complaining the Symptoms Recur or infection recur .

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General Treatment For Cbp

Treating CBP is challenging, because only few oral antibiotics could penetrate the prostate and achieve sufficient effective bactericidal concentration at the field of infection . A reproducible rat model of CBP has shown that the acinar and interstitial spaces are the most susceptible part of infection . Thus, pathogens at prostatic secretion and tissues must be exposed to a sufficiently high concentration of antibiotics for effective therapy that would inhibit bacterial growth or eradicate pathogens from the site of infection . In addition, with the emergence of multidrug resistance and/or ESBLs-producing bacteria, biofilm-producing bacteria and the shift in bacterial etiology, the therapeutic schemes of CBP become complex and tricky .

Treatment algorithm for chromic bacterial prostatitis. . *Combination therapy: Plant extracts combinate with antibiotics, antibiotics combinate with antibiotics and other drug combinate with antibiotics.

Treating Prostatitis Not Caused By Infection

Why Aren’t Antibiotics Helping Chronic Prostatitis?

Chronic non-bacterial prostatitis, also known as chronic pelvic pain syndrome , is inflammation of the prostate without any detectable infection. The cause is unknown, making it difficult to treat.

Even though no bacteria are implicated in this kind of prostatitis, a physician will sometimes prescribe antibiotics in case there is a hidden infection. Most often, however, therapy involves treating the symptoms. Options include:

  • Over-the-counter pain medications like ibuprofen or naproxen
  • Soaking in a hot bath
  • Medications such as phenazopyridine , oxybutynin, or tolterodine to help with frequent, urgent, or painful urination
  • Psychological counseling to help with the ongoing pain

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What Is The Prognosis For A Prostate Infection

The prognosis for acute bacterial prostatic infections is usually good if treated appropriately with effective antibiotics. The prognosis for chronic bacterial prostatic infections is less or only fair because the recurrent disease is difficult to cure, and the cure rate is less than the acute type.

  • No evidence suggests that any prostate infections increase the risk of urinalysis.
  • Only a few men with acute bacterial prostatitis develop chronic bacterial prostatitis. After patients recover, their doctor should evaluate their upper urinary tract.
  • Only half of the men with chronic bacterial prostatitis will be cured . Relapses are common and may lead to psychological problems, especially depression.

What Is A Prostate Infection

A prostate infection occurs when your prostate and the surrounding area become inflamed. The prostate is about the size of a walnut. Its located between the bladder and the base of the penis. The tube that moves urine from the bladder to the penis runs through the center of your prostate. The urethra also moves semen from the sex glands to the penis.

Several types of infections can affect the prostate. Some men with prostatitis experience no symptoms at all, while others report many, including intense pain.

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How Do Doctors Diagnose A Prostate Infection

The diagnosis of both acute and chronic prostate infections begins with the history of the symptoms described above, the physical exam, including the digital exam of the prostate and often confirmed by culture and identification of the infecting organism.

Acute bacterial prostatitis diagnosis

  • Usually an enlarged, firm, and tender prostate is enough to make a presumptive diagnosis and start treatment .
  • Because there is usually a low level of bacteria in urine, the doctor will perform a urinalysis to quantitate and identify infecting bacteria by urine culture.
  • If the person has symptoms suggesting the infection has spread outside the prostate , blood cultures and other blood tests are likely to be ordered.
  • If a spread of the infection is suspected, a doctor will often perform an ultrasound to help confirm the diagnosis and to rule out an abscess. If this ultrasound is not available, the doctor may perform a CT scan or MRI of the pelvis.

Chronic bacterial prostatitis diagnosis

One of two tests are sometimes performed to help with the diagnosis:

The classic test is a Meares-Stamey 3-glass test. Three separate urine samples are collected and examined during this test. The last sample is taken after prostatic massage.

Premassage and postmassage test

Men with recurrent urinary tract infections should have ultrasound imaging of their upper urinary tract and a plain abdominal X-ray or an intravenous urography to exclude a possible structural problem or a kidney stone.

What Causes Chronic Prostatitis/chronic Pelvic Pain Syndrome

Prostatitis treatment Bactrim

Chronic prostatitis/CPPS is a persistent discomfort or pain that you feel in your lower pelvic region – mainly at the base of your penis and around your anus. It is usually diagnosed if you have had pain for at least three months within the previous six months. The cause of this type of chronic prostatitis is not fully understood.

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How Effective Is Ciprofloxacin For Prostatitis

Prostatitis is the inflammation of the prostate gland, commonly occurring in males and responsible for 8% of urologist visits in the United States. This ailment may cause extreme discomfort and originates from a number of sources, including bacterial infection. When infection is present, doctors often prescribe a course of antibiotics to help fend off bacteria and return the body to health. Ciprofloxacin is a commonly utilized antibiotic however, due to its bacteria-specific effectiveness, ciprofloxacin for prostatitis may range from nominally to extremely successful.

Ciprofloxacin belongs to a class of antibiotics known as fluoroquinolones. Drugs from this class act to interfere with DNA sequencing in undesirable bacteria, causing the cessation of bacterial reproduction and subsequently returning the body to baseline health. There are a number of bacterial strains that are susceptible to ciprofloxacin and a number that are resistant. For this reason, it is important that the specific type of bacteria responsible for infection be determined prior to using ciprofloxacin for prostatitis.

Treating Prostatitis Effectively: A Challenge For Clinicians

Nhuan Nguyen, PharmD, MBA, CHEClinical PharmacistGR Health, Georgia Regents Medical CenterAugusta, GeorgiaCharlie Norwood VA Medical CenterAugusta, GeorgiaUniversity of Georgia College of PharmacyAthens, Georgia

US Pharm. 2014 39:35-40.

ABSTRACT: Prostatitis, which affects 5% to 9% of males and occurs mostly in middle age, is classified based on signs and symptoms, with urinary urgency, frequency, and pain typical in nearly all categories. Most physicians are not familiar with prostatitis, particularly chronic prostatitis associated with chronic pelvic pain syndrome . Accordingly, patients are often misdiagnosed and receive ineffective treatment, resulting in poor quality of life. CP/CPPS is challenging to treat, as its causes are not clearly defined and the antibiotics used for therapy have low effective rates. Clinical pharmacists can contribute significantly to patient care by advising physicians and other medical professionals regarding drug efficacy, adverse drug reactions, and drug interactions, and by assisting in the selection of optimal antibiotics and/or treatment regimens for prostatitis.

Prostatitis , which occurs in 5% to 9% of males aged 18 years and older, most often develops in middle age.1 In the early 1990s, prostatitis accounted for about 1% and 8% of office visits to family practitioners and urologists, respectively.1

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How Are Bacterial Forms Of Prostatitis Managed Or Treated

Antibiotics can kill bacteria that cause bacterial types of prostatitis. Men with acute bacterial prostatitis may need 14 to 30 days of antibiotics, starting with IV antibiotics in the hospital. Rarely, men need surgery to drain an abscess on the prostate.

Treating chronic bacterial prostatitis is challenging. You may need up to three months of antibiotics to sterilize the prostate. If the prostate cant be sterilized, low-dose antibiotics can be used long term to prevent recurrences. Some men need surgery to remove prostate stones or scar tissue in the urethra. Rarely, surgeons remove part or all of the prostate gland .

Patient Disposition And General Characteristics

Recognizing Prostatitis vs Prostate Cancer | Ask a Prostate Expert, Mark Scholz, MD

Between 12 January 2007 and 21 April 2009, 471 patients were screened with the MearesStamey 4-glass’ test and 63 pathogen-negative patients were excluded from the trial. Four hundred and eight patients who were pathogen-positive, were randomized and treated with either levofloxacin or ciprofloxacin according to the intention-to-treat principle. The mean age of the patients was 33.4 years in levofloxacin group and 33.5 years in ciprofloxacin group. Of these, 209 and 199 patients, respectively, completed the 4-week treatment phase. At the end of the study at visit 6, results for 209 patients in the levofloxacin-treated group and 199 patients in the ciprofloxacin-treated group were evaluated. The general characteristics , clinical symptoms and signs, pathogenesis of chronic prostatitis, and episodes during the last 12 months were similar in both groups. Twenty-two patients in the levofloxacin-treated group and 20 in the ciprofloxacin-treated group used additional agents to treat their prostatitis.

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Levaquin Prostatitis Antibiotic :

Levaquin or Levofloxacin is an Fluoroquinolone Antibiotic generally Prescribed to the Patients Suffering from Prostatitis Conditions Such As Acute Bacterial prostatitis or Chronic Bacterial Prostatitis .

Directions Of Usage Of Levaquin For Prostatitis : Levaquin Comes in 3 Different forms Tablet , Syrup , IV . Tablets are Taken Once a Day Orally can be taken along with the water , Syrup is also should be taken once a day orally , IV Intravenous Infusion can be taken according to the Physicians Directions or under the Supervision of A Physician .

Levaquin Is Prescribed For :ï¬ Pneumonia or Other Respiratory Infectionsï¬ COPD â Chronic Sbstructive Pulmonary Diseaseï¬ Infections Related to Heart Valves / Endocarditisï¬ Tuberculosisï¬ STD â Sexually Transmitted Diseases mostly bacterialï¬ UTI â Urinary Tract Infections mostly bacterialï¬ Kidney Infectionsï¬ Anthrax

You Can Not Take Levaquin If you Are Suffering From : Patients with Previous Signs of Reaction to Levaquin or Levofloxacin or Fluoroquinolone Antibiotics Are Not Allowed To take the Medication , Please consult your Physician Before you start any Antibiotic medication . Self Diagnosis Can Lead to Serious Health Complications even Death .

Does Prostatitis Cause Cancer

Although prostatitis can cause you trouble, it does not cause cancer. There is a blood test some doctors use for prostate cancer called the prostate-specific antigen test . If you have prostatitis, your PSA level might go up. This does not mean you have cancer. Your doctor will treat your prostatitis and may check your PSA level again.

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