Risk Factors For Post
Youre at a greater risk for post-treatment Lyme disease syndrome if youre infected by the bite of a diseased tick. If the infection progresses to the chronic stage, your symptoms might continue for weeks, months, or even years after the initial tick bite.
You may also be at a higher risk for these long-term symptoms if youre not treated with the recommended antibiotics. However, even people who receive antibiotic therapy are at risk. Because the cause of post-treatment Lyme disease syndrome is unknown, theres no way to determine whether it will progress to the chronic stage.
Typically, the symptoms of post-treatment Lyme disease syndrome resemble those that occur in earlier stages. People with persistent symptoms often experience lingering episodes of:
- fatigue
A Reasonable Approach To Post
If you are being treated for PTLD, there is no magic bullet to treat this problem, but here are some important steps to consider:
- Choose a doctor you trust and who can work closely with you.
- If your doctor agrees to start antibiotics for several months, make sure you talk about the risks and cost, as this can be dangerous and expensive.
- Make sure not to rely solely on antibiotics. The evidence for a benefit from antibiotics is weak, and we rely mostly on physicians clinical experience and interest in the disease to design a personalized therapeutic plan. For some, a more holistic approach may be the way to go.
- If you try supplements, ask about their source and purity, as they are not FDA-regulated.
- Consider looking for services in medical school hospitals or clinics where they may have programs with ongoing research on how to diagnose and treat Lyme.
Natural Remedies For The Chronic Inflammation Of Lyme Disease
Everyone knows that inflammation isnt good, especially when it becomes chronic. But to do something about it, you need to understand whats driving the inflammation in the first place.
Though you cant actually see chronic inflammation, you can certainly feel it. It manifests as joint discomfort, stiffness, general achiness, fatigue, low stamina, brain fog, slow mental activity, depressed mood, and all the other symptoms associated with chronic Lyme disease. Simply put, you feel inflamed.
The root of inflammation is excessive turnover of cells. We all lose cells, and up to a certain point, its perfectly normal. Cells in the body are constantly wearing out, getting injured, or being invaded by microbes. In fact, we typically lose 50-70 billion cells every day. While much of cellular turnover is accounted for by cells that are shed from the body, such as skin and intestinal cells, tissues inside the body are losing cells, too.
When cells die, they break apart and create debris. If enough debris collects in tissues, it obstructs the flow of water, nutrients, and oxygen that cells need to stay healthy. At the same time, metabolic waste produced by cells is trapped around the cell, which, of course, isnt a good thing. If enough debris collects, cells start to choke in their own waste.
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What If I Don’t Feel Better After Treatment
If you’re treated for Lyme disease and don’t feel better after youve finished your treatment, talk to your doctor. He or she may recommend a longer course of antibiotics or may be able to prescribe another medication to help with symptoms like joint or muscle pain.
You might also want to seek a second opinion, especially if your Lyme disease diagnosis was not initially confirmed via a two-step blood test. If your body has not responded to antibiotics, its possible that something else besides the bacteria that causes Lyme disease is making you sick. In 2017, for example, the CDC reported on a woman who was given antibiotics and herbal remedies to treat her chronic Lyme disease, when she actually hadand eventually died fromamyotrophic lateral sclerosis .
Even if you do recover completely from a Lyme disease diagnosis, your immune system may continue making antibodies to fight Lyme disease bacteria for months or even years after the infection is gone. Those antibodies wont protect you from getting a second Lyme disease infection, however, so be sure to take steps to protect yourself from ticks in the future.
Who Gets Lyme Disease
Anyone bitten by an infected deer tick can get Lyme disease. Most U.S. cases of Lyme disease happen in Connecticut, Delaware, Maine, Maryland, Massachusetts, Minnesota, New Hampshire, New Jersey, New York, Pennsylvania, Rhode Island, Vermont, Virginia, and Wisconsin. But Lyme disease is found in other parts of the U.S., Europe, Asia, and Australia too.
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Who’s At Risk And Where Are Ticks Found
The risk of getting Lyme disease is higher:
- for people who spend time in woodland or moorland areas
- from March to October because more people take part in outdoor activities
Ticks are found throughout the UK and in other parts of Europe and North America. There are a high number of ticks in the Scottish Highlands.
It’s thought only a small proportion of ticks carry the bacteria that cause Lyme disease. Being bitten doesn’t mean you’ll definitely be infected. However, it’s important to be aware of the risk and speak to a GP if you start to feel unwell.
Treating Lyme Without Antiobiotics 18 Months Later
Ive been treating Lyme without antibiotics for about 18 months. For some, that might sound like an eternity. For those who have been struggling with Lyme, you probably know thats really not a lot of time to be treating this horrific disease.
I still dont know all of the answers. But I do know, that a no-antibiotics approach to Lyme treatment has worked remarkably well for me.
After 18 months, I am probably about 80% better. Im pretty ecstatic about the progress Ive made. I feel blessed that Ive experienced this much healing. Early on, I hit Lyme really hard. I did absolutely everything my doctor suggested. It was a lot. It was expensive. But it paid off.
You can read more here
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Possible Complications To Watch For With Lyme Disease
Talk to your veterinarian if you have any questions or concerns about your dogs condition.
- Some dogs who take antibiotics can develop loss of appetite, vomiting and diarrhea.
- Once infected, a dog will always have the bacteria that cause Lyme disease in his or her body. Therefore, relapses are possible, and owners should be on the lookout for unexplained fever, swollen lymph nodes, and/or lameness.
- A small percentage of dogs develop kidney failure as a result of Lyme disease. Clinical signs include vomiting, weight loss, poor appetite, lethargy, increased thirst and urination, and abnormal accumulations of fluid within the body.
The Chance Of Getting Lyme Disease
Not all ticks in England carry the bacteria that causes Lyme disease.
But it’s still important to be aware of ticks and to safely remove them as soon as possible, just in case.
Ticks that may cause Lyme disease are found all over the UK, but high-risk places include grassy and wooded areas in southern and northern England and the Scottish Highlands.
Ticks are tiny spider-like creatures that live in woods, areas with long grass, and sometimes in urban parks and gardens. They’re found all over the UK.
Ticks do not jump or fly. They attach to the skin of animals or humans that brush past them.
Once a tick bites into the skin, it feeds on blood for a few days before dropping off.
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Can Chronic Lyme Be Cured Dr Christine Green Answers Your Questions
Christine Green, MD, is a Stanford-trained, board-certified family medicine physician with 30 years of experience treating patients with tick-borne illness.
On the board of LymeDisease.org, Dr. Green is also Co-director of Education for Invisible International,, is on Bay Area Lyme Foundations Scientific Advisory Board and has served on the Education Committee for ILADS.
In this Q& A, she discusses common questions asked by patients about diagnosing and treating Lyme and other tick-borne diseases.
Quinine Derivatives To Boost Intracellular Antibiotics
Intracellular
Inside of cells, Lyme may live in cave-like structures called vacuoles. In these vacuoles, Lyme germs create a hostile acidic environment that can limit the effectiveness of various antibiotics. Quinine derivatives, like hydroxychloroquine , can make the inside of cells more basic which can help the tetracyclines and macrolides mentioned above work better.
- Hydroxychloroquine 200 mg 1 pill 2 times a day
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Antimicrobials That Kill Growing Phase Cysts
Intracellular and Extracellular
Note: I work with the following agents as anti-cyst agents based on the mechanism by which these antibiotics work and some scientific experiments. For the Rifamycins, there are no laboratory experiments showing these agents work against cysts. Clinically, I see great benefit in using the Rifamycins as my anti-cyst agents – so I list them here.
Rifamycins
- Rifampin 300 mg 2 pills 1 time a day or 1 pill 2 times a day
- Rifabutin 150 mg 2 pills 1 time a day
Azoles
- Tinidazole 500 mg 1 pill 2 or three times a day usually pulsed for four days on then three days off of each 7 days
- Metronidazole 500 mg 1 pill 2 or three times a day usually pulsed for four days on then three days off of each 7 days.
Herbal
- Grapefruit seed extract 250 mg 1 pill 2 times a day. Note this is an herbal antibiotic that I find as effective as the prescription options in this list.
Questions To Ask Your Doctor
- I found a tick embedded in my skin, but I cant get it out. What should I do?
- Ive been bitten by a tick. Do I need to be seen?
- Do I need a blood test to confirm Lyme disease?
- Which antibiotic is best for me?
- How long will I have to take the antibiotic?
- What tick or insect repellent should I use for me or my child?
- How long will the symptoms last?
- What should I do if I still dont feel well a long time after I was bitten?
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Diagnosis Testing And Treatment
You may have heard that the blood test for Lyme disease is correctly positive only 65% of the time or less. This is misleading information. As with serologic tests for other infectious diseases, the accuracy of the test depends upon how long youve been infected. During the first few weeks of infection, such as when a patient has an erythema migrans rash, the test is expected to be negative.
Several weeks after infection, FDA cleared tests have very good sensitivity.
It is possible for someone who was infected with Lyme disease to test negative because:
If you are pregnant and suspect you have contracted Lyme disease, contact your physician immediately.
- Report being bitten by a tick, or
- Live in, or have recently visited, a tick-infested area.
What Causes Lyme Disease
Lyme disease is caused by infection with the spirochete Borrelia burgdorferi. In regions of the U.S. where Lyme disease is common, risk factors for getting bitten by a tick include:
- Spending a lot of time outdoors
- Proximity to areas between forest land and lawns, particularly if the area contains low-lying grasses or shrubs
Ticks can also attach to pets who may bring them into the home. The pet may become infected with Lyme disease. If the tick does not attach to the pet, it can attach to a human and transmit the infection.
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When To See A Doctor
A person should see a doctor if they have recently received a tick bite. It is not possible to know whether a tick is carrying Lyme disease, and the symptoms may take weeks to appear.
The earlier a person receives a diagnosis and treatment, the higher the likelihood of a quick and complete recovery.
It is not always possible for a person to tell if a tick has bitten them. As such, people should also see a doctor if they experience any Lyme disease symptoms. A doctor will ask about the persons symptoms and duration and whether the person has spent time in tick-infested areas.
Treatment Within 30 Days Of Initial Tick Bite
Studies show that 80 to 90% of people, who take a two to three week course of antibiotics within 30 days after a known acute tick bite, do not develop chronic Lyme disease. Based on my experience, these people are cured of Lyme disease – they will not have further problems with Lyme disease, unless they get a new tick bite.
For the best chance of cure in acute Lyme, I found doxycycline to works best in my Seattle practice. But if a person cannot take doxycycline, cefuroxime or amoxicillin is an option. These are the three antibiotics recommended by the United States Centers for Disease Control and the Infectious Diseases Society of America. In my experience, I find these work better in an acute setting than herbal antibiotics at getting a cure.
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How To Remove A Tick
A tick must remain attached to the skin for at least 36 hours to spread Lyme disease. The best way of preventing Lyme disease is to remove a tick as soon as possible.
The blacklegged tick that spreads disease-causing bacteria resembles a tiny spider. Young ticks are around the size of a poppy seed, while adult ticks are around the size of a sesame seed. Ticks of all ages are reddish-brown.
Below are some steps for tick removal.
- Step 1: Use fine-tipped tweezers to gently grasp the tick near its head or mouth. Avoid squeezing the tick.
- Step 2: Using the tweezers, pull the tick carefully and steadily away from the skin. Avoid yanking or twisting the tick, as this could cause its mouthparts to remain in the skin.
- Step 3: After removing the tick, dispose of it by putting it in some alcohol or flushing it down the toilet.
- Step 4: Apply antiseptic to the tick bite.
How To Prevent Post
While you may not be able to prevent post-treatment Lyme disease syndrome, you can take precautions to prevent coming into direct contact with infected ticks. The following practices can reduce your likelihood of getting Lyme disease and developing persistent symptoms.
If a tick bites you, contact your doctor. You should be observed for 30 days for signs of Lyme disease. You should also learn the signs of early Lyme disease and seek prompt treatment if you think youre infected. Early antibiotic intervention may reduce your risk of developing chronic symptoms.
The signs of early Lyme disease can occur from 3 to 30 days after a bite from an infected tick. Look for:
- a red, expanding bulls-eye rash at the site of the tick bite
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How Long Does Lyme Disease Last
Lyme disease symptoms can begin anywhere from three to 30 days after transmission of the infection from a tick. If treated early on with antibiotics, most people feel better within a few weeks, says Dr. Zemel.
According to the CDC, its not uncommon for people to experience lingering symptoms like fatigue and joint or muscle pain for a few weeks or months after treatment. Additional antibiotics wont help these symptoms, however, and most people improve on their own over time.
In a small percentage of cases, people continue to experience symptoms for more than six months after their recommended course of antibiotics is completed. This is sometimes referred to as chronic Lyme diseasebut that name is misleading, says Dr. Kuritzkes, because there is no evidence that the bacteria that causes Lyme disease is still present in the body. Instead, the CDC refers to this condition as post-treatment Lyme disease syndrome .
As with many other kinds of infectious diseases, some people are left with some debilitating symptoms that dont go away, says Dr. Kuritzkes. I like to compare it to polio: Some people who had polio are left paralyzed, but that doesnt mean they have chronic polio they have permanent damage from the infection, even after its gone away.
Its possible that Lyme infection leads to some damage that we dont fully understand yet, Dr. Kuritzkes adds. But we do know that long-term or repeated courses of antibiotics have no benefit in these cases.
How Do Patients Respond To Treatment
We looked at patients with chronic Lyme diseasethose who remained ill for six or more months following treatment with antibiotics for Lyme disease . The first thing we did was identify different patients as well, high responders, low responders, or non-responders. Well patients responded positively to a survey question asking if they were well or remained ill. Those who remained ill were asked whether their condition had changed as a result of treatment. Those who said they were unchanged or worse were categorized as non-responders. Patients who said that they were better or worse following treatment, were asked how much better or worse. Those who had improved substantially were deemed high responders.
59% of patients had improved with treatment and 42% were either well or high responders. The focus of our study was on this latter group. You might wonder whether 42% response is considered good compared to other drugs. Heres what the prior head of GlaxoSmithKline said about treatment effectiveness rates of drugs in general .
The vast majority of drugs more than 90 per cent only work in 30 or 50 per cent of the people. Drugs out there on the market work, but they dont work in everybody. Dr. Allen Roses, GlaxoSmithKline
So you can see that a 42% rate of substantial improvement is within the range of most drugs on the market.
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