Before Taking This Medicine
Kyleena can increase your risk of developing a serious pelvic infection, which may threaten your life or your future ability to have children. Ask your doctor about this risk.
Do not use Kyleena during pregnancy. If left in place during pregnancy, the IUD could cause severe infection, miscarriage, premature birth, or death of the mother. The hormone in Kyleena may also cause unwanted effects in a female newborn.
Tell your doctor right away if you become pregnant. If you continue the pregnancy, watch for signs such as fever, chills, cramps, vaginal bleeding or discharge.
You should not use Kyleena if you are allergic to levonorgestrel, silicone, silica, silver, barium, iron oxide, or polyethylene, or if you have:
abnormal vaginal bleeding that has not been checked by a doctor
an untreated or uncontrolled pelvic infection
pelvic inflammatory disease , unless you had a normal pregnancy after the infection was treated and cleared
uterine fibroid tumors or conditions that affect the shape of the uterus
past or present cancer of the breast, cervix, or uterus
liver disease or liver tumor
if you have another intrauterine device in place
if you had an abortion or miscarriage in the past 6 weeks or
if you gave birth to a baby in the past 6 weeks.
Tell your doctor if you have ever had:
How Birth Control Pills Work
Birth control pills are a form of hormonal contraception meant to prevent pregnancy. Most birth control pills contain the two hormones estrogen and progesterone. This helps block the release of eggs from the ovary, or ovulation. Some birth control pills, such as the minipill, help thicken cervical mucus to make it more difficult for sperm to reach an unfertilized egg.
Can Antibiotics Affect My Birth Control
Does amoxicillin affect birth control? I used this antibiotic for my throat.
Nope! Antibiotics like amoxicillin wont change the effectiveness of your birth control. The antibiotic rifampin is the only exception it can lower the effectiveness of the pill, patch, and ring. So unless youre using one of those birth control methods and taking rifampin, which is a medicine used to treat tuberculosis, theres nothing to worry about.
There are, however, some other medicines besides antibiotics that can make birth control not work as well. So its very important to be open and honest with your nurse or doctor about what medicines youre on no matter if it was prescribed or not so they can give you the best care.
Planned Parenthood delivers vital reproductive health care, sex education, and information to millions of people worldwide. Planned Parenthood Federation of America, Inc. is a registered 501 nonprofit under EIN 13-1644147. Donations are tax-deductible to the fullest extent allowable under the law.
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Oral Contraceptive Steroid Pharmacokinetics
The estrogens most commonly found in oral contraceptive preparations are ethinylestradiol and mestranol, a prodrug which is metabolized to ethinylestradiol. After metabolism via the first pass effect, ethinylestradiol has an oral bioavailability of 40% to 50% . Hydroxylation is the main metabolic pathway for ethinylestradiol, whereas conjugation is considered to be a minor pathway in most women, resulting in sulphation or glucuronidation of the original estrogenic steroid. Glucuronide and sulphate conjugates reach the small intestine by way of the bile duct. Hydrolytic enzymes of intestinal bacteria break the conjugates down, resulting in the release of free, active estrogenic hormone. The active hormone is then available for reabsorption and undergoes enterohepatic cycling, which is responsible for plasma estrogen levels necessary for contraception.
The progestins present in oral contraceptive pills also undergo conjugation. Hydrolysis of conjugates leads to the formation of inactive metabolites because the parent molecule cannot be directly conjugated. Progestins are not thought to undergo extensive enterohepatic cycling and are, thus, less likely to be involved in drug interactions with antibiotics than ethinylestradiol .
Mirena Insertion And Removal
Women can have Mirena birth control inserted during a regular doctors visit. Mirena insertion takes about five minutes.
Doctors use a few tools to help insert the device but the insertion is not considered surgery.
Women should wait at least seven days after the start of their period to insert Mirena. Women who have just given birth, had a miscarriage or an abortion should wait at least six weeks.
A doctor or other trained health provider can remove Mirena at any time.
Eight out of 10 women who have had their Mirena IUD removed can get pregnant within a year, according to Bayers Mirena Handbook.
Health care providers must remove Mirena if it moves out of place. If a patient is not pregnant, she can get a new IUD inserted.
How To Prevent Birth Control Ineffectiveness
Always talk with your doctor about birth control interactions before taking new medications, including vitamins or over-the-counter medications. Ask if the medication or supplement will interfere with your birth control effectiveness. Even if more research is needed, its generally better to err on the side of caution. You can use backup forms of birth control in addition to oral contraceptives when taking medications that interfere with the effectiveness.
If you forget to use a backup method, you can take over-the-counter emergency contraception for up to five days after intercourse. For long term medications, such as retrovirals, diabetes medications, or anticonvulsants, it is best to talk with your provider about other contraception methods, such as long-acting reversible contraception or injectable progesterone.
Do Antibiotics Make An Iud Less Effective
According to the NHS, most antibiotics do not affect contraception.
To date, the only types of antibiotic proven to impact hormonal contraception and may potentially make it less effective are rifampicin-like antibiotics which include rifampicin and rifabutin.
These drugs can be used to treat diseases, including tuberculosis and other bacterial infections. Medications interfering with birth control is more commonly seen with some types of hormonal contraception, including the pill, the vaginal ring, or the patch.
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The Primary Benefit Of Getting A Copper Iud Is Pregnancy Prevention
Its important to acknowledge that there are lots of reasons to explore birth control options . That said, there are health benefits to birth control that extend beyond making pregnancy less likely. Theres evidence to suggest that hormonal birth control can regulate periods reduce the risk of endometrial, ovarian, and colorectal cancers and reduce pelvic pain from conditions like endometriosis, among other benefits, according to the American College of Obstetricians and Gynecologists . This is because of estrogen and progestin, the hormones in various forms of hormonal birth control, the ACOG explains. Since the copper IUD doesnt contain hormones, the main benefit of using it is contraception. But, lets be honest, preventing pregnancy is a major benefit.
You Can Actually Use The Copper Iud As Emergency Contraception
Many people dont realize this, but the copper IUD is an effective form of emergency contraception as long as its inserted within five days after unprotected sex, according to the ACOG. A 2012 meta-analysis published in the journal Human Reproduction looked at 42 studies and found that the copper IUD had a pregnancy rate of only 0.09% when it was used as a form of emergency contraception.
The copper IUD causes inflammation in the uterine lining and may prevent implantation of the developing embryo, Dr. Worly explains.
Of course, this isnt necessarily the most convenient form of emergency contraception. If you werent planning on getting an IUD, pill-based forms might make more sense for you depending on how easily youre able to access them versus an intrauterine device.
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The Risk Of Expulsion And Perforation Are Very Low But They Do Occasionally Happen
IUDs come with a small risk of expulsion, which is when your body starts to push the IUD out of you. There isnt a ton of research on this out there, but the average expulsion incidence rate is between 2 to 10% of users, the ACOG says. Risk factors include recently having had the IUD inserted, getting it placed right after childbirth, and history of heavy or prolonged periods, among others. Though you dont really need to stress about this possibility, if it were to happen to you, you might experience symptoms like bleeding and cramping, feel something hard coming from your cervix, or see the IUD somewhere outside of your body however, it is possible to experience an expulsion without any major symptoms.
IUDs can also cause perforation, which is when the device pushes through the wall of your uterus. It sounds alarming, but again, the risk is really low. According to a 2015 study published in the journal Conception, out of 61,448 people who had an IUD, only 20 with the copper form experienced a perforation. In fact, perforation most often happens due to an error during placement. Much like with expulsion, this isnt something that needs to keep you up at night, but if you were dealing with perforation, you would potentially experience pelvic pain , though you might not experience any major symptoms at all.
The Copper Iud Is Hormone
Since the copper IUD doesnt contain hormones, you can use it in situations where other kinds of birth control may not be a fit. For instance, it might be a good choice for breastfeeding people, Taraneh Shirazian, M.D., assistant professor in the department of obstetrics and gynecology at NYU Langone Medical Center, tells SELF. This is because theres a slight chance that estrogen, which is in forms of combined hormonal birth control like the pill, patch, and ring, may impact your milk supply, according to the ACOG.
Due to its lack of estrogen, the copper IUD may also offer an advantage for some people who have health conditions that can get worse when exposed to this hormone, such as people with a history of blood clots, or high blood pressure , Dr. Shirazian says.
If youre not able to tolerate hormones for some reason, definitely mention that to your doctor when trying to find which type of IUD is right for you.
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Does The Mirena Iud Lose Effectiveness When On Antibiotics L
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Drugs or herbal products that induce enzymes, including CYP3A4, that metabolize progestins may decrease the serum concentrations of progestins.
Some drugs or herbal products that may decrease the serum concentration of levonorgestrel include:
Significant changes in the serum concentrations of the progestin have been noted in some cases of co-administration with HIV protease inhibitors or with non-nucleoside reverse transcriptase inhibitors.
Consult the labeling of all concurrently used drugs to obtain further information about interactions with Mirena or the potential for enzyme alterations.
This is from the Mirana IUD Website. Thought it would be useful as some drugs CAN affect the IUD.
What If My Healthcare Provider Prescribes Rifampin For Me
If your healthcare provider does prescribe rifampin to you, be sure to let them know if you are using a hormonal contraceptive.
Unless otherwise stated by your healthcare provider, you can still continue to take your pills as usual every day. However, during this time, itâs important to use non-hormonal birth control methods, like external or internal condoms, or abstain from sex as backup protection during rifampin treatment .
If you use birth control pills, consider following the recommendations for what to do if you miss two or more pills:
Continue to use these non-hormonal backup methods for 7 days after you stop taking rifampin, provided you still have 7 hormone-containing pills left in your pack
If there are fewer than 7 hormonal pills left in the pack after you stop taking rifampin, skip the hormone-free pills and start a new pack, but still continue to use back-up contraception for the first 7 pills of the pack .
If you are using another form of hormonal contraceptive, like the patch or ring, speak to your healthcare provider.
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How Does Mirena Removal Affect Fertility
Most womens fertility will go back to normal after Mirena removal, and they can get pregnant quickly. If a woman does not want to get pregnant after having an IUD removed, she should use another form of birth control.
We found no difference in 12-month pregnancy rates or time to pregnancy between former IUD users and users of other contraceptive methods. However, there was a clinically and statistically significant reduction in fertility in African American women.
Are There Any Side Effects From Using The Hormonal Iud
Possible side effects include:
- When it is first inserted some users have period-type cramping that usually settles after a few days.
- Sometimes the IUD can come out. This is more common in the first 3 months of it being inserted.
- Your period will change. Spotting or frequent bleeding is common in the first 3 to 6 months. By 6 months around 95% of users will have a light regular period or no bleeding at all .
- You may experience tender breasts, headaches, skin changes and mood changes. These side effects nearly always settle with time. The hormonal IUD has not been shown to cause weight gain.
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What Medications Make Mirena Less Effective
Some medications and herbal supplements are known to interact with the Mirena IUD. These may include substances like anti-anxiety drugs, anti-seizure medications or anticonvulsants, and blood thinners like warfarin.
Some antibiotics and St. Johns Wort, which is an herbal supplement sometimes used to treat symptoms of depression and mood disorders, may also possibly interact with Mirena.
Report Problems With Your Medications To The Fda
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.
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What Are The Differences Between Kyleena Mirena And Skyla
Kyleena, Mirena, and Skyla are all T-shaped contraceptive devices that slowly release levonorgestrel and are placed inside a womans uterus to prevent pregnancy. The main differences between them are how long they last for, how much levonorgestrel they release, and the size of the device.
For more information about the differences between Kyleena, Mirena, and Skyla, see here.
- Will antibiotics stop my contraception working? NHS
- Reminder: Most broad-spectrum antibiotics do not interact with combined oral contraceptives BPAC BPJ Issue 61.
- Simmons KB, Haddad LB, Nanda K, Curtis KM. Drug interactions between non-rifamycin antibiotics and hormonal contraception: a systematic review. Am J Obstet Gynecol. 2018 Jan 218:88-97.e14. DOI: 10.1016/j.ajog.2017.07.003. Epub 2017 Jul 8. PMID: 28694152.
Timing Of Removal If You Wish To Avoid Pregnancy
Scotchie says you can remove an IUD at any time. But if you want to prevent pregnancy right away, you need to use another form of contraception such as condoms or birth control pills until you want to become pregnant.
Talk with your doctor ahead of time to determine the right method of birth control for you. Examples of other reversible methods include:
- oral contraceptives
- birth control implant or shot
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What Happens If I Get Pregnant While Im Using An Iud
If you become pregnant while you are using an IUD, it is important that you see a doctor or nurse as soon as possible and have the IUD removed. The doctor or nurse will also need to rule out a pregnancy in your fallopian tubes .
If the IUD is removed, you can choose to continue or terminate the pregnancy . If the IUD is not removed and you continue with the pregnancy, there is a higher risk of losing the pregnancy or delivering the baby early.
Will Emergency Contraception Like Plan B Work If I Am On These Medications
Emergency contraception like Plan B may not work if you:
Weigh over 165 pounds
Take anti-seizure medications, antibiotics for TB, HIV medications, or St. Johns Wort
Have recently used anti-seizure medications, antibiotics for TB, HIV medications, or St. Johns Wort
In these cases, the best method of emergency contraception is the copper IUD, for example, ParaGard. This will need to be inserted by a trained healthcare professional within 5 days of having unprotected sex. For more information about emergency contraception, see our blog post here.
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